Police are appealing for public assistance to help locate missing 13-year-old Epping teen Jackson May.

Jackson was last seen at a residential address on Polydor Ct, Epping, on Tuesday (Oct. 17).

Police have concerns for his welfare due to his age and the length of time he has been missing.

Investigators believe Jackson may be frequenting the Mill Park, South Morang, Bundoora, Preston, and Melbourne CBD areas.

He is believed to be travelling on the public transport system.

Jackson is described as being Caucasian in appearance, approximately 160cm tall with a thin-medium build, brown eyes, and brown hair.

He was last seen wearing blue Nike sneakers.

Anyone with information about Jackson is asked to contact the Mill Park Police Station on 9407 3333.