Police are continuing to appeal for public assistance to help locate missing Don Valley man Edward Fitzpatrick.

The 42-year-old left Maroondah Hospital at 1.10pm on Tuesday, April 9, and was last sighted a short time later near Ringwood East Railway Station.

He has not been seen or made contact with family since.

He is described as being Caucasian in appearance, of thin build, 183cm tall, with tanned skin and sandy coloured thinning hair.

He is believed to be travelling on public transport.

Police and family have concerns for his welfare due to medical conditions that require medication.

He is known to frequent the Wandin, Seville, Yarra Junction and Ringwood areas.

Anyone who sights Edward or has information on his current whereabouts is urged to contact Ringwood Police Station on 9871 3000.